Comprobación del Efecto Hipoglucemiante del Extracto del Fruto de la Tuna (Opuntia ficus-indica) en Ratones (Mus musculus) con Hiperglucemia Inducida.

Abstract

The objective of this thesis is to test the hypoglycemic effect of the aqueous extract of the prickly pear fruit (Opuntia ficus-indica) in 18 mice (Mus musculus) with induced hyperglycemia, divided into six groups that during the research work were called Target, Positive Control, Negative Control, Extract at 100%, 70% and 40%. To check the hypoglycemic activity, the extracts at different percentages were administered to the corresponding groups one hour after the sucrose overload. The scientific analytical methods were used, and for the analysis of the data obtained, the ANOVA, T-student and Turkey tests at 5% were used. The results obtained at the end of this research work were: the group corresponding to the White group maintained normal glucose values, the positive and negative control group, the 100%, 70% and 40% extract returned to normal glucose values 12 hours after the administration of the sucrose overload. It can be concluded that the aqueous extract of prickly pear fruit at different percentages does have a hypoglycemic effect. A phase called Acute Toxicity was also carried out in the present investigation, in which it was assured that the extracts do not affect the health of the consumer. After this study was carried out, it was concluded that the extracts in their different percentages do not have a toxic effect.