Elaboración de un plan piloto para el desarrollo del sistema de farmacovigilancia dirigido a pacientes de hospitalización en el Área de Medicina Interna, del Hospital José María Velasco Ibarra de Tena.

Abstract

It was carried out a pilot plan for the development of Pharmacovigilance system for patients in the area of internal medicine of José María Velasco Ibarra Hospital in Tena during the period November 2015 - January 2016. An intensive Pharmacovigilance system was implemented, focused on 75 patients, using tools such as review of medical records, daily medical visits, interviews with the patient, and tab drug making for the report of adverse reactions. In the same way a retrospective study of the diseases most often recorded in the service was performed, obtaining that the prevalent diseases are: diabetes mellitus type II, hypertension, renal failure, pneumonia and paraquat poisoning, consequently, the medical personnel was surveyed to determine the medications often prescribed for these pathologies. The interpretation of the results was performed through frequency analysis where 48 cases of ADR, which represents 64%. Women had a higher percentage of ADR (69%). ADRs were classified according to Naranjo´s algorithm corresponding to 90% probable category, followed by the possible category with 5%. The presence of ADR is associated with chronic diseases and age. It was possible to develop the system of Pharmacovigilance identifying presence of ADR in this service using the yellow card, identifying through research the reality of the population, so it is recommended to continue training health personnel on Pharmacovigilance and emphasizing how important this is in the Pharmaceutical Biochemist area.