Evaluación de la actividad antiinflamatoria del extracto de Allpa Atsera (Lepidium Bipinnatifidum) mediante el Test de Edema Inducido en ratas (Rattus Novergicus)

Abstract

The purpose of the study was to verify the antiinflammatory activity of the extract of Allpa atsera (lepidium bipinnatifidum) by means of the edema test induced in rats (rattus norvegicus), carried out in the Phytochemical Laboratory of the Faculty of Sciences of the Polytechnic School of Chimborazo, The purpose of giving an alternative to the usi of anti-inflammatory drugs. The quality control of the raw material and the extract of Allpa atsera (lepidium bipinnatifidum) was evaluated for anti-inflammatory activity, the anti-inflammatory effect was evaluated in 22 albino rats of Wistart strain randomly divided into 6 groups of 3 Rats each. 1 ml was administered orally. Of the solutions, BG (white), GN (negative control, GP (positive control), groups with treatment: GE1 (ethanolic extract 20% plus carrageenan 1%), GE2 (ethanolic extract 40% plus carrageenan 1%), and GE3 (80% ethanolic extract plus carrageenan 1%). The volume of inflammation of the right rat leg was measured from 0 to 6 hors, the results were analyzed with ANOVA and Tuckey HSD tests with a 95% (Lepidium bipinnatifidum) at 80% have antiinflammatory activity identical to that of naproxen sodium and is safe. It is recommended that a phytopharmaceutical Of the extract of Allpa atsera (lepidium bipinnatifidum) to facilitate administration.