Implementación del Modelo de Gestión del Sistema de Farmacovigilancia en el Subcentro de salud Cambo-Chimborazo

Abstract

The Pharmacovigilance System Management Model was implemented in the Chambo Health Sub-center in the province of Chimborazo, in order to apply the National Pharmacovigilance System Regulations (SNFV), which are mandatory for health facilities to identify, evaluate and prevent suspected adverse drug reactions (ADRs). To evaluate the implementation of the system, a pilot program was carried out with 30 patients diagnosed with arterial hypertension between 46 and 91 years of age. The method used to search for ADRs was active pharmacovigilance by means of which we detected 15 ADRs distributed as follows: 13.33% of the patients presented some ADR to ARA II, followed by calcium antagonist with 6.66%, ACEI, beta-blocker, psycholeptic and lipid inhibitor with 3.33% respectively. The algorithm of Karch and Lasagna modified by Naranjo et al. was applied to classify the ADRs with 46.67% in the DOUBTFUL category, 3.33% POSSIBLE, 20% PROBABLE and finally 0% in the PROVEN category. The application of the Pharmacovigilance System is beneficial, since it is possible to detect, evaluate and prevent ADRs, it also contributed to patient adherence to pharmacological treatment which helps to improve quality of life. It is recommended that teamwork be encouraged so that this model is permanently applied because the operation of the Pharmacovigilance System is the responsibility of all health professionals.