Elaboración de una crema con actividad cicatrizante a base de extracto hidroalcóholico de hojas de Piper aduncum L.

Abstract

The objective of the present study was to produce a cream with cicatrizing action, based on hydroalcoholic extract of leaves of Piper Aduncum L. The plants were collected at Tena city, which is located in Napo province. The vegetable material was disinfected, dried, and crushed. A control of quality was carried out through different tests such as humidity determination, total ash determination, and water-soluble and insoluble hydrogen chloride. The dried and crushed vegetable material with éter was macerated for 48 hours, 96% of distilled water, and 70% of alcohol. Besides, phytochemical tests were applied on each extract for the qualitative determination of secondary metabolites which are relevant for products such as flavonoids, tannins, and triterpenes. Then different formulas were used to obtain the final formula of the product. Phytochemical features were evaluated. Finally, they were packed and labeled. A microbiological analysis was carried out in which it was demonstrated the lack of different microorganisms such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, total coliforms, Mesophilic aerobiosis, mold, and yeast, obtaining a final product of high quality for its consumption. In conclusion, a cicatrizing cream was obtained which presented every established parameter within the limits. For the next studies, it is recommended to make the verification of the cicatrizing action in experimental animals. Besides, some combinations with different organic excipients that can enhance cicatrizing action should be carried out. This can improve the cosmetic presentation.