Alteraciones del metabolismo óseo en pacientes diabéticos tipo 2 con enfermedad renal crónica, hospital IESS Latacunga. Año 2018

Abstract

The following research work determined the bone and mineral metabolism alterations in patients with chronic kidney disease and type 2 diabetes mellitus at the IESS Latacunga Hospital in the period January 2018 - December 2018. Data are obtained from the patient's medical records admitted, during that period a descriptive, cross-sectional period study was carried out, in which fifty-four patients were evaluated, who were hospitalized in the internal medicine service due to complications of these pathologies. This study focuses on the determination of the main complications, the association that exists between the values of parathyroid hormone (PTH), alkaline phosphatase, total calcium, serum phosphorus, creatinine, glomerular filtration rate (GFR), stratification of renal failure, age and sex in patients diagnosed with type 2 diabetes mellitus and chronic kidney disease. t was found that the main alterations of bone metabolism are the presence of calcifications in aortic arch (14.81%), osteodegenerative changes and / or signs of bone demineralization (18.52%), 2 or more imaging alterations (5.56%) and other non-imaging alterations. or there were no complications (61.1%). 52% of the studied patients belong to the masculine sex and 48% to the feminine sex, the age in which there are more alterations of the bone metabolism oscillates between the 61 and 80 years of age. The stage of renal failure in which more alterations occur is in the IIIa stage. When identifying the main complications among the study population, it is proposed to unify efforts to prevent their progression among people and thus reduce their prevalence.